› 8rzv

X-ray diffraction
1.51Å resolution

Structure of UP1 S4ES6E phosphomimetic mutant in complex with human telomeric repeat DNA

Released:
DOI: 10.2210/pdb8rzv/pdb
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PDB entry 8rzv coloured by chain, front view.
PDB entry 8rzv coloured by chain, side view.
PDB entry 8rzv coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Dunnett L, Prischi F

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-270711 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 198 amino acids
Theoretical weight: 22.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P09651 (Residues: 2-195; Coverage: 52%)
Gene names: HNRNPA1, HNRPA1
Sequence domains: RNA recognition motif
DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 12 nucleotides
Theoretical weight: 3.77 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P43212
Unit cell:
a: 51.12Å b: 51.12Å c: 173.27Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.196 0.22
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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