› 8sd3

Electron Microscopy
2.95Å resolution

CryoEM structure of rat Kv2.1(1-598) wild type in nanodiscs

Released:
DOI: 10.2210/pdb8sd3/pdb
PDB entry 8sd3 coloured by chain, front view.
PDB entry 8sd3 coloured by chain, side view.
PDB entry 8sd3 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Inactivation of the Kv2.1 channel through electromechanical coupling.
Fernández-Mariño AI, Tan XF, Bae C, Huffer K, Jiang J, Swartz KJ
OpenAccess logo Nature (2023)
PMID: 37758949
Related structures: EMD-40349

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-229899 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium voltage-gated channel subfamily B member 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 600 amino acids
Theoretical weight: 68.59 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: P15387 (Residues: 5-602; Coverage: 70%)
Gene name: Kcnb1
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand POV 24 x POV
Ligand K 4 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.95Å
Relevant EMDB volumes: EMD-40349
Expression system: Homo sapiens

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