› 8sdh

X-ray diffraction
2.84Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-248635 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike protein S1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 205 amino acids
Theoretical weight: 23.1 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P0DTC2 (Residues: 333-530; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
Neutralizing antibody CC25.56 Heavy Chain Chains: C, H
Molecule details ›
Chains: C, H
Length: 223 amino acids
Theoretical weight: 23.77 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Neutralizing antibody CC25.56 Light Chain Chains: D, L
Molecule details ›
Chains: D, L
Length: 214 amino acids
Theoretical weight: 22.79 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: C2
Unit cell:
a: 171.052Å b: 105.586Å c: 98.993Å
α: 90° β: 117.31° γ: 90°
R-values:
R R work R free
0.248 0.246 0.283
Expression systems:
  • Trichoplusia ni
  • Homo sapiens

Quick links

Citations

1 review citation

The D Gene in CDR H3 Determines a Public Class of Human Antibodies to SARS-CoV-2.
Yuan et al. (2024)