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Cryo-EM Structure of RyR1 + ADP (Local Refinement of TMD)

Source organism: Oryctolagus cuniculus
Biochemical function: disordered domain specific binding
Biological process: cellular response to caffeine
Cellular component: ryanodine receptor complex

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF02026
Domain description: RyR domain
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8sew contains 16 copies of Pfam domain PF02026 (RyR domain) in Ryanodine receptor 1. Showing 4 copies in chain A (this domain is out of the observed residue ranges!).

PF00622
Domain description: SPRY domain
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8sew contains 12 copies of Pfam domain PF00622 (SPRY domain) in Ryanodine receptor 1. Showing 3 copies in chain A (this domain is out of the observed residue ranges!).

PF01365
Domain description: RIH domain
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8sew contains 8 copies of Pfam domain PF01365 (RIH domain) in Ryanodine receptor 1. Showing 2 copies in chain A (this domain is out of the observed residue ranges!).

PF00520
Domain description: Ion transport protein
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8sew contains 4 copies of Pfam domain PF00520 (Ion transport protein) in Ryanodine receptor 1. Showing 1 copy in chain A.

PF06459
Domain description: Ryanodine Receptor TM 4-6
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8sew contains 4 copies of Pfam domain PF06459 (Ryanodine Receptor TM 4-6) in Ryanodine receptor 1. Showing 1 copy in chain A.

PF08454
Domain description: RyR and IP3R Homology associated
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8sew contains 4 copies of Pfam domain PF08454 (RyR and IP3R Homology associated) in Ryanodine receptor 1. Showing 1 copy in chain A.

PF21119
Domain description: Ryanodine receptor junctional solenoid repeat
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8sew contains 4 copies of Pfam domain PF21119 (Ryanodine receptor junctional solenoid repeat) in Ryanodine receptor 1. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF02815
Domain description: MIR domain
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8sew contains 4 copies of Pfam domain PF02815 (MIR domain) in Ryanodine receptor 1. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF08709
Domain description: Inositol 1,4,5-trisphosphate/ryanodine receptor
Occurring in:
  1. Ryanodine receptor 1
The deposited structure of PDB entry 8sew contains 4 copies of Pfam domain PF08709 (Inositol 1,4,5-trisphosphate/ryanodine receptor) in Ryanodine receptor 1. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

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