Function and Biology Details
Reactions catalysed:
Endonucleolytic cleavage to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end-products
RNA = a 5'-hydroxy-ribonucleotide + n nucleoside-2',3'-cyclophosphates
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-270723 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
1 distinct RNA molecule
2 distinct DNA molecules
1 distinct RNA molecule
Macromolecules (4 distinct):
CRISPR-associated endonuclease Cas12a
Molecule details ›
Chain: A
Length: 1311 amino acids
Theoretical weight: 151.71 KDa
Source organism: Acidaminococcus sp. BV3L6
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Length: 1311 amino acids
Theoretical weight: 151.71 KDa
Source organism: Acidaminococcus sp. BV3L6
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
U2UMQ6 (Residues: 1-1307; Coverage: 100%)
Sequence domains:
