8sga

X-ray diffraction
1.9Å resolution

Crystal structure of 770E11, a monoclonal antibody isolated from a human Epstein-Barr virus seropositive donor

Released:
Source organism: Homo sapiens
Entry authors: Chen WH, Jensen JL, Joyce MG

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-243225 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
770E11 Fab light chain Chain: L
Molecule details ›
Chain: L
Length: 212 amino acids
Theoretical weight: 22.2 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
770E11 Fab heavy chain Chain: H
Molecule details ›
Chain: H
Length: 226 amino acids
Theoretical weight: 23.82 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 42.14Å b: 73.08Å c: 132.45Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.206 0.242
Expression system: Homo sapiens