› 8sk8

Electron Microscopy
2.31Å resolution

human liver mitochondrial Glutamate dehydrogenase 1

Released:
DOI: 10.2210/pdb8sk8/pdb
PDB entry 8sk8 coloured by chain, front view.
PDB entry 8sk8 coloured by chain, side view.
PDB entry 8sk8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology.
Zhang Z, Tringides ML, Morgan CE, Miyagi M, Mears JA, Hoppel CL, Yu EW
OpenAccess logo Mol Cell Proteomics 22 100666 (2023)
PMID: 37839702
Related structures: EMD-40558

Function and Biology Details

Reaction catalysed: 
L-glutamate + H(2)O + NAD(P)(+) = 2-oxoglutarate + NH(3) + NAD(P)H
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132442 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate dehydrogenase 1, mitochondrial Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 558 amino acids
Theoretical weight: 61.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P00367 (Residues: 1-558; Coverage: 100%)
Gene names: GLUD, GLUD1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.31Å
Relevant EMDB volumes: EMD-40558

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