EC 2.4.1.212: Hyaluronan synthase
Reaction catalysed:
UDP-alpha-D-glucuronate + N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-(nascent hyaluronan) = UDP + beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-(nascent hyaluronan)
Systematic name:
Alternating UDP-N-acetyl-alpha-D-glucosamine:beta-D-glucuronosyl-(1->3)-(nascent hyaluronan) 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-(nascent hyaluronan) 3-beta-D-glucuronosyltransferase (configuration-inverting)
Alternative Name(s):
- Alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-(nascent hyaluronan) 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-(nascent hyaluronan) 3-beta-D-glucuronosyltransferase
- HAS
- SeHAS
- SpHAS