8sr6

X-ray diffraction
2.22Å resolution

Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (3-17)peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-178651 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SET domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 451 amino acids
Theoretical weight: 51.92 KDa
Source organism: Legionella pneumophila subsp. pneumophila
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5ZUS4 (Residues: 84-532; Coverage: 82%)
Gene names: legAS4, lpg1718
Sequence domains:
Histone H3.3C Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.59 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q6NXT2 (Residues: 4-18; Coverage: 11%)
Gene names: H3-5, H3F3C

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08B1-1
Spacegroup: P3121
Unit cell:
a: 69.32Å b: 69.32Å c: 196.01Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.185 0.23
Expression systems:
  • Escherichia coli
  • Not provided