8src

Electron Microscopy
2.92Å resolution

Cryo-EM structure of TRPM2 chanzyme in the presence of Calcium and ADP-ribose

Released:
Source organism: Salpingoeca rosetta
Related structures: EMD-40726

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
PDBe Complex ID:
PDB-CPX-271142 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nudix hydrolase domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 1494 amino acids
Theoretical weight: 168.25 KDa
Source organism: Salpingoeca rosetta
Expression system: Homo sapiens
UniProt:
  • Canonical: F2UB89 (Residues: 1-1494; Coverage: 100%)
Gene name: PTSG_05449
Sequence domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.92Å
Relevant EMDB volumes: EMD-40726
Expression system: Homo sapiens