› 8sxn

Electron Microscopy
4.04Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-239967 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine/threonine-protein kinase Nek7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 302 amino acids
Theoretical weight: 34.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8TDX7 (Residues: 1-302; Coverage: 100%)
Gene name: NEK7
Sequence domains: Protein kinase domain
NACHT, LRR and PYD domains-containing protein 3 Chains: C, D
Molecule details ›
Chains: C, D
Length: 910 amino acids
Theoretical weight: 103.68 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q96P20 (Residues: 133-1036; Coverage: 87%)
Gene names: C1orf7, CIAS1, NALP3, NLRP3, PYPAF1
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand 7YN 2 x 7YN
Ligand ATP 2 x ATP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.04Å
Relevant EMDB volumes: EMD-40855
Expression systems:
  • Escherichia coli
  • Spodoptera frugiperda

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