› 8sza

Electron Microscopy
2.75Å resolution

Cryo-EM Structure of NINJ1 Filament at 2.75 Angstrom Resolution

Released:
DOI: 10.2210/pdb8sza/pdb
PDB entry 8sza coloured by chain, front view.
PDB entry 8sza coloured by chain, side view.
PDB entry 8sza coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
How NINJ1 mediates plasma membrane rupture and why NINJ2 cannot
Sahoo B, Mou Z, Liu W, Dubyak G, Dai X
Biorxiv (2023)
Related structures: EMD-40905

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-217101 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ninjurin-1 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 177 amino acids
Theoretical weight: 19.28 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q92982 (Residues: 2-152; Coverage: 99%)
Gene name: NINJ1
Sequence domains: Ninjurin

Ligands and Environments

1 bound ligand:
Ligand CLR 6 x CLR
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.75Å
Relevant EMDB volumes: EMD-40905
Expression system: Homo sapiens

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