GO terms
Biochemical function:
- temperature-gated ion channel activity
- phosphoprotein binding
- metal ion binding
- identical protein binding
- phosphatidylinositol binding
- chloride channel regulator activity
- intracellularly gated calcium channel activity
- ligand-gated monoatomic ion channel activity
- monoatomic cation transmembrane transporter activity
- lipid binding
- ATP binding
- calmodulin binding
- protein binding
- calcium channel activity
- monoatomic cation channel activity
- excitatory extracellular ligand-gated monoatomic ion channel activity
- extracellular ligand-gated monoatomic ion channel activity
- monoatomic ion channel activity
- transmembrane signaling receptor activity
Biological process:
- cellular response to nerve growth factor stimulus
- response to capsazepine
- calcium ion import across plasma membrane
- negative regulation of establishment of blood-brain barrier
- cellular response to temperature stimulus
- cellular response to acidic pH
- cellular response to growth factor stimulus
- cellular response to tumor necrosis factor
- cellular response to cytokine stimulus
- cellular response to ATP
- cellular response to alkaloid
- calcium ion transmembrane transport
- smooth muscle contraction involved in micturition
- excitatory postsynaptic potential
- transmembrane transport
- protein homotetramerization
- detection of chemical stimulus involved in sensory perception of pain
- detection of temperature stimulus involved in sensory perception of pain
- detection of temperature stimulus involved in thermoception
- thermoception
- sensory perception of mechanical stimulus
- sensory perception of taste
- behavioral response to pain
- response to pain
- positive regulation of nitric oxide biosynthetic process
- response to peptide hormone
- positive regulation of apoptotic process
- cellular response to heat
- monoatomic ion transmembrane transport
- calcium-mediated signaling
- sensory perception of pain
- urinary bladder smooth muscle contraction
- glutamate secretion
- negative regulation of mitochondrial membrane potential
- negative regulation of heart rate
- response to heat
- response to pH
- positive regulation of cytosolic calcium ion concentration
- calcium ion transport
- monoatomic ion transport
- lipid metabolic process
- negative regulation of systemic arterial blood pressure
- peptide secretion
- diet induced thermogenesis
- microglial cell activation
- fever generation
- temperature homeostasis
- negative regulation of transcription by RNA polymerase II
Protein families (Pfam)![The deposited structure of PDB entry 8t10 contains 8 copies of Pfam domain PF00023 (Ankyrin repeat) in Transient receptor potential cation channel subfamily V member 1. Showing 2 copies in chain B [auth A] (this domain is out of the observed residue ranges!).](https://www.ebi.ac.uk/pdbe/static/entry/8t10_1_A_Pfam_PF00023_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>8t10</span> contains 8 copies of Pfam domain <span class='highlight'>PF00023 (Ankyrin repeat)</span> in <span class='highlight'>Transient receptor potential cation channel subfamily V member 1</span>. Showing 2 copies in chain <span class='highlight'>B [auth A]</span> (this domain is out of the observed residue ranges!).")
![The deposited structure of PDB entry 8t10 contains 4 copies of Pfam domain PF00520 (Ion transport protein) in Transient receptor potential cation channel subfamily V member 1. Showing 1 copy in chain B [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/8t10_1_A_Pfam_PF00520_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>8t10</span> contains 4 copies of Pfam domain <span class='highlight'>PF00520 (Ion transport protein)</span> in <span class='highlight'>Transient receptor potential cation channel subfamily V member 1</span>. Showing 1 copy in chain <span class='highlight'>B [auth A]</span>.")