› 8t18

Electron Microscopy
2.6Å resolution

Cryo-EM structure of dodecameric hub domain of CaMKII beta

Released:
DOI: 10.2210/pdb8t18/pdb
PDB entry 8t18 coloured by chain, front view.
PDB entry 8t18 coloured by chain, side view.
PDB entry 8t18 coloured by chain, top view.
Source organisms:
Primary publication:
Hub stability in the calcium calmodulin-dependent protein kinase II.
Chien CT, Puhl H, Vogel SS, Molloy JE, Chiu W, Khan S
Commun Biol 7 766 (2024)
PMID: 38918547
Related structures: EMD-40957

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-245741 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase type II subunit beta; Green fluorescent protein Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 407 amino acids
Theoretical weight: 45.63 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P42212 (Residues: 2-238; Coverage: 100%)
  • Canonical: P08413 (Residues: 409-542; Coverage: 25%)
Gene names: Camk2b, GFP
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.6Å
Relevant EMDB volumes: EMD-40957
Expression system: Escherichia coli

Quick links