› 8t21

Electron Microscopy
3.6Å resolution

Cryo-EM structure of mink variant Y453F trimeric spike protein

Released:
DOI: 10.2210/pdb8t21/pdb
PDB entry 8t21 coloured by chain, front view.
PDB entry 8t21 coloured by chain, side view.
PDB entry 8t21 coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Primary publication:
Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2.
Ahn H, Calderon BM, Fan X, Gao Y, Horgan NL, Jiang N, Blohm DS, Hossain J, Rayyan NWK, Osman SH, Lin X, Currier M, Steel J, Wentworth DE, Zhou B, Liang B
J Med Virol 95 e29163 (2023)
PMID: 37842796
Related structures: EMD-40977

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-232585 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1269 amino acids
Theoretical weight: 140.24 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A6H1PJZ3 (Residues: 1-1208; Coverage: 95%)
Gene name: S
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-40977
Expression system: Homo sapiens

Quick links

Citations

1 mention without citation

Isotopy classes for 3-periodic net embeddings.
Power et al. (2020)