8t5c

Electron Microscopy
4.7Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero undecamer (preferred)
PDBe Complex ID:
PDB-CPX-238037 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (13 distinct):
Glycoprotein G1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 202 amino acids
Theoretical weight: 22.88 KDa
Source organism: Lassa virus Josiah
Expression system: Homo sapiens
UniProt:
  • Canonical: P08669 (Residues: 59-207, 208-257; Coverage: 41%)
Gene names: GP-C, GPC
Sequence domains: Arenavirus glycoprotein
Glycoprotein G2 Chains: a, b, c
Molecule details ›
Chains: a, b, c
Length: 194 amino acids
Theoretical weight: 22.14 KDa
Source organism: Lassa virus Josiah
Expression system: Homo sapiens
UniProt:
  • Canonical: P08669 (Residues: 260-418; Coverage: 32%)
Gene names: GP-C, GPC
Sequence domains: Arenavirus glycoprotein
D5 nanobody Chain: D
Molecule details ›
Chain: D
Length: 120 amino acids
Theoretical weight: 13.23 KDa
Source organism: Camelus bactrianus
Expression system: Homo sapiens
8.11G Heavy Chain Chains: E, H
Molecule details ›
Chains: E, H
Length: 120 amino acids
Theoretical weight: 13.26 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
8.11G Light Chain Chains: I, L
Molecule details ›
Chains: I, L
Length: 109 amino acids
Theoretical weight: 12.1 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.7Å
Relevant EMDB volumes: EMD-41048
Expression system: Homo sapiens