› 8t6q

Electron Microscopy
3.5Å resolution

Cryo-EM structure of dodecameric CaMKII beta holoenzyme T287A T306A T307A

Released:
DOI: 10.2210/pdb8t6q/pdb
PDB entry 8t6q coloured by chain, front view.
PDB entry 8t6q coloured by chain, side view.
PDB entry 8t6q coloured by chain, top view.
Source organisms:
Primary publication:
Hub stability in the calcium calmodulin-dependent protein kinase II.
Chien CT, Puhl H, Vogel SS, Molloy JE, Chiu W, Khan S
OpenAccess logo Commun Biol 7 766 (2024)
PMID: 38918547
Related structures: EMD-41077

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-245741 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase type II subunit beta; Green fluorescent protein Chains: A, B, C, D, F, G, H, I, J, K, L, N
Molecule details ›
Chains: A, B, C, D, F, G, H, I, J, K, L, N
Length: 815 amino acids
Theoretical weight: 90.85 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P42212 (Residues: 2-238; Coverage: 100%)
  • Canonical: P08413 (Residues: 1-542; Coverage: 100%)
Gene names: Camk2b, GFP
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-41077
Expression system: Escherichia coli

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