› 8tan

Electron Microscopy
3.05Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-238836 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Insulin-like growth factor 1 receptor alpha chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 952 amino acids
Theoretical weight: 108.94 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P08069 (Residues: 31-935; Coverage: 68%)
Gene name: IGF1R
Sequence domains:
Insulin-like domain-containing protein Chain: C
Molecule details ›
Chain: C
Length: 64 amino acids
Theoretical weight: 6.8 KDa
Source organism: Mandarin fish ranavirus
Expression system: Not provided
UniProt:
  • Canonical: A0A3G5APE9 (Residues: 16-79; Coverage: 81%)
Gene name: ORF110L
Sequence domains: Insulin/IGF/Relaxin family

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
1 bound ligand:
Ligand NAG 11 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.05Å
Relevant EMDB volumes: EMD-41138
Expression systems:
  • Cricetulus griseus
  • Not provided

Quick links