› 8tb2

X-ray diffraction
1.88Å resolution

Structure of SasG (type II) (residues 165-421) from Staphylococcus aureus MW2

Released:
DOI: 10.2210/pdb8tb2/pdb
PDB entry 8tb2 coloured by chain, front view.
PDB entry 8tb2 coloured by chain, side view.
PDB entry 8tb2 coloured by chain, top view.
Source organism: Staphylococcus aureus subsp. aureus MW2
Primary publication:
Staphylococcus aureus skin colonization is mediated by SasG lectin variation.
Mills KB, Maciag JJ, Wang C, Crawford JA, Enroth TJ, Keim KC, Dufrêne YF, Robinson DA, Fey PD, Herr AB, Horswill AR
Cell Rep 43 114022 (2024)
PMID: 38568806

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-244274 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative surface protein MW2416 Chain: A
Molecule details ›
Chain: A
Length: 262 amino acids
Theoretical weight: 28.82 KDa
Source organism: Staphylococcus aureus subsp. aureus MW2
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8NUV0 (Residues: 165-421; Coverage: 20%)
Gene name: MW2416
Sequence domains: Bacterial lectin

Ligands and Environments

4 bound ligands:
Ligand SO4 4 x SO4
Ligand CA 2 x CA
Ligand NA 1 x NA
Ligand ZN 3 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21212
Unit cell:
a: 78.6Å b: 70.21Å c: 43.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.184 0.253
Expression system: Escherichia coli BL21(DE3)

Quick links