Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero 26-mer (preferred)
PDBe Complex ID:
PDB-CPX-272419 (preferred)
Entry contents:
9 distinct polypeptide molecules
Macromolecules (9 distinct):
Large tegument protein deneddylase
Molecule details ›
Chains: A, C
Length: 2241 amino acids
Theoretical weight: 253.54 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
Sequence domains: Herpesvirus tegument protein, N-terminal conserved region
Length: 2241 amino acids
Theoretical weight: 253.54 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
- Canonical:
P16785 (Residues: 1-2241; Coverage: 100%)
Sequence domains: Herpesvirus tegument protein, N-terminal conserved region
Inner tegument protein
Molecule details ›
Chains: B, D
Length: 983 amino acids
Theoretical weight: 110.23 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
Sequence domains: Herpes virus tegument protein U30
Length: 983 amino acids
Theoretical weight: 110.23 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
- Canonical: P16784 (Residues: 1-983; Coverage: 100%)
Sequence domains: Herpes virus tegument protein U30
Capsid vertex component 2
Molecule details ›
Chains: E, F
Length: 642 amino acids
Theoretical weight: 71.27 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
Sequence domains: Herpesvirus UL25 family
Length: 642 amino acids
Theoretical weight: 71.27 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
- Canonical: P16726 (Residues: 1-642; Coverage: 100%)
Sequence domains: Herpesvirus UL25 family
Capsid vertex component 1
Molecule details ›
Chain: G
Length: 594 amino acids
Theoretical weight: 68.57 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
Sequence domains: Herpesvirus UL17 protein
Length: 594 amino acids
Theoretical weight: 68.57 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
- Canonical: P16799 (Residues: 1-594; Coverage: 100%)
Sequence domains: Herpesvirus UL17 protein
Major capsid protein
Molecule details ›
Chains: H, I, J, K, L, M
Length: 1370 amino acids
Theoretical weight: 154.05 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
Sequence domains: Herpes virus major capsid protein
Length: 1370 amino acids
Theoretical weight: 154.05 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
- Canonical: P16729 (Residues: 1-1370; Coverage: 100%)
Sequence domains: Herpes virus major capsid protein
Small capsomere-interacting protein
Molecule details ›
Chains: N, O, P, Q, R, S
Length: 75 amino acids
Theoretical weight: 8.5 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
Sequence domains: Small capsid protein of Herpesviridae
Length: 75 amino acids
Theoretical weight: 8.5 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
- Canonical: Q7M6N6 (Residues: 1-75; Coverage: 100%)
Sequence domains: Small capsid protein of Herpesviridae
Triplex capsid protein 1
Molecule details ›
Chains: T, W
Length: 290 amino acids
Theoretical weight: 33.07 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
Sequence domains: Herpesvirus capsid shell protein VP19C
Length: 290 amino acids
Theoretical weight: 33.07 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
- Canonical: P16783 (Residues: 1-290; Coverage: 100%)
Sequence domains: Herpesvirus capsid shell protein VP19C
Triplex capsid protein 2
Molecule details ›
Chains: U, V, X, Y
Length: 306 amino acids
Theoretical weight: 34.64 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
Sequence domains: Herpesvirus VP23 like capsid protein
Length: 306 amino acids
Theoretical weight: 34.64 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
- Canonical: P16728 (Residues: 1-306; Coverage: 100%)
Sequence domains: Herpesvirus VP23 like capsid protein
Large structural phosphoprotein
Molecule details ›
Chain: Z
Length: 1048 amino acids
Theoretical weight: 112.83 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
Sequence domains: Herpesvirus large structural phosphoprotein UL32
Length: 1048 amino acids
Theoretical weight: 112.83 KDa
Source organism: Human herpesvirus 5 strain AD169
UniProt:
- Canonical: P08318 (Residues: 1-1048; Coverage: 100%)
Sequence domains: Herpesvirus large structural phosphoprotein UL32
