8tgo

X-ray diffraction
5.75Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentadecamer (preferred)
PDBe Complex ID:
PDB-CPX-558220 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (10 distinct):
Transmembrane protein gp41 Chains: B, H, a
Molecule details ›
Chains: B, H, a
Length: 164 amino acids
Theoretical weight: 17.86 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
35O22 scFv Chains: D, L, b
Molecule details ›
Chains: D, L, b
Length: 286 amino acids
Theoretical weight: 30.34 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
PGT124 light chain Chains: C, P, c
Molecule details ›
Chains: C, P, c
Length: 214 amino acids
Theoretical weight: 23.06 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Envelope glycoprotein gp160 Chains: G, R, e
Molecule details ›
Chains: G, R, e
Length: 490 amino acids
Theoretical weight: 54.16 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
PGT124 heavy chain Chains: O, S, f
Molecule details ›
Chains: O, S, f
Length: 235 amino acids
Theoretical weight: 25.35 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-1
Spacegroup: C2
Unit cell:
a: 357.592Å b: 212.044Å c: 207.71Å
α: 90° β: 125.07° γ: 90°
R-values:
R R work R free
0.244 0.242 0.292
Expression system: Homo sapiens