8tgw

Electron Microscopy
3.6Å resolution

Cryo-EM structure of 1059 SOSIP trimer purified via Galanthus nivalis lectin chromatography

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-275766 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Envelope glycoprotein gp160 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 491 amino acids
Theoretical weight: 55.39 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: B2YXU4 (Residues: 28-516; Coverage: 57%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
Transmembrane protein gp41 Chains: a, b, c
Molecule details ›
Chains: a, b, c
Length: 153 amino acids
Theoretical weight: 17.26 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: B2YXL9 (Residues: 517-669; Coverage: 18%)
Gene name: env
Sequence domains: Retroviral envelope protein

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: BMA
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-41246
Expression system: Homo sapiens