› 8thd

Electron Microscopy
3.25Å resolution

Structure of the Saccharomyces cerevisiae clamp unloader Elg1-RFC bound to PCNA

Released:
DOI: 10.2210/pdb8thd/pdb
PDB entry 8thd coloured by chain, front view.
PDB entry 8thd coloured by chain, side view.
PDB entry 8thd coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structure of the PCNA unloader Elg1-RFC.
Zheng F, Yao NY, Georgescu RE, Li H, O'Donnell ME
OpenAccess logo Sci Adv 10 eadl1739 (2024)
PMID: 38427736
Related structures: EMD-41254

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-246611 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Telomere length regulation protein ELG1 Chain: A
Molecule details ›
Chain: A
Length: 791 amino acids
Theoretical weight: 91.39 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: Q12050 (Residues: 1-791; Coverage: 100%)
Gene names: ELG1, O3510, RTT110, YOR144C, YOR3510C
Replication factor C subunit 4 Chain: B
Molecule details ›
Chain: B
Length: 323 amino acids
Theoretical weight: 36.2 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P40339 (Residues: 1-323; Coverage: 100%)
Gene names: O0923, RFC4, YOL094C
Sequence domains:
Replication factor C subunit 3 Chain: C
Molecule details ›
Chain: C
Length: 336 amino acids
Theoretical weight: 37.84 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38629 (Residues: 1-336; Coverage: 99%)
Gene names: N0533, RFC3, YNL290W
Sequence domains:
Replication factor C subunit 2 Chain: D
Molecule details ›
Chain: D
Length: 353 amino acids
Theoretical weight: 39.79 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P40348 (Residues: 1-353; Coverage: 100%)
Gene names: J1808, RFC2, YJR068W
Sequence domains:
Replication factor C subunit 5 Chain: E
Molecule details ›
Chain: E
Length: 354 amino acids
Theoretical weight: 39.99 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P38251 (Residues: 1-354; Coverage: 100%)
Gene names: RFC5, YBR0810, YBR087W
Sequence domains:
Proliferating cell nuclear antigen Chains: F, G, H
Molecule details ›
Chains: F, G, H
Length: 260 amino acids
Theoretical weight: 29.1 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P15873 (Residues: 1-258; Coverage: 100%)
Gene names: POL30, YBR0811, YBR088C
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand AGS 4 x AGS
Ligand MG 3 x MG
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.25Å
Relevant EMDB volumes: EMD-41254
Expression system: Saccharomyces cerevisiae

Quick links