› 8thq

X-ray diffraction
2.41Å resolution

Function and Biology Details

Reaction catalysed: 
Endonucleolytic cleavage to 5'-phosphomonoester
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-278851 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Protein argonaute-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 127 amino acids
Theoretical weight: 14.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UKV8 (Residues: 227-352; Coverage: 15%)
Gene names: AGO2, EIF2C2
Sequence domains: PAZ domain
RNA (5'-R(*CP*GP*UP*GP*AP*CP*UP*CP*U)-3') Chains: R, S
Molecule details ›
Chains: R, S
Length: 9 nucleotides
Theoretical weight: 2.81 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P65
Unit cell:
a: 91.936Å b: 91.936Å c: 69.579Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.215 0.284
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

PDB-REDO

The sliders below show the change in model quality between original PDB entry and the PDB-REDO entry

Model Geometry
 
 
Data not available
DNA/RNA Geometry
 
 
Data not available
Fit model/data
 
 
Data not available
PDB-REDO