› 8ti5

X-ray diffraction
1.15Å resolution

Crystal structure of Tyr p 36.0101

Released:
DOI: 10.2210/pdb8ti5/pdb
PDB entry 8ti5 coloured by chain, front view.
PDB entry 8ti5 coloured by chain, side view.
PDB entry 8ti5 coloured by chain, top view.
Source organism: Tyrophagus putrescentiae
Primary publication:
Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity.
O'Malley A, Sankaran S, Carriuolo A, Khatri K, Kowal K, Chruszcz M
Biol Chem (2024)
PMID: 38662449

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-268862 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Profilin Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 14.41 KDa
Source organism: Tyrophagus putrescentiae
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A1B2YLJ4 (Residues: 2-131; Coverage: 99%)
Sequence domains: Profilin

Ligands and Environments

1 bound ligand:
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P3121
Unit cell:
a: 55.364Å b: 55.364Å c: 78.814Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.15 0.148 0.171
Expression system: Escherichia coli

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Citations

1 review citation

Can Physicochemical Properties Alter the Potency of Aeroallergens? Part 1 - Aeroallergen Protein Families.
Teixeira et al. (2024)