› 8tin

Electron Microscopy
4Å resolution

Human ACKR3 phosphorylated by GRK2 in complex with Arrestin3 reconstructed without receptor/micelle

Released:
DOI: 10.2210/pdb8tin/pdb
PDB entry 8tin coloured by chain, front view.
PDB entry 8tin coloured by chain, side view.
PDB entry 8tin coloured by chain, top view.
Source organisms:
Entry authors: Chen Q, Tesmer JJG
Related structures: EMD-41296

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-284250 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Fab7 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 240 amino acids
Theoretical weight: 25.72 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
Beta-arrestin-2 Chain: A
Molecule details ›
Chain: A
Length: 392 amino acids
Theoretical weight: 44.11 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P32120 (Residues: 1-403; Coverage: 93%)
  • Best match: P32120-2 (Residues: 1-392)
Gene name: ARRB2
Sequence domains:
Fab7 light chain Chain: L
Atypical chemokine receptor 3 Chain: R

Ligands and Environments

No bound ligands
2 modified residues:
Ligand TPO 1 x TPO
Ligand SEP 1 x SEP

Experiments and Validation Details

Entry percentile scores
Resolution: 4Å
Relevant EMDB volumes: EMD-41296
Expression systems:
  • Escherichia coli
  • Spodoptera frugiperda

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