› 8tj5

Electron Microscopy
6.6Å resolution

Inner spoke ring of the yeast NPC

Released:
DOI: 10.2210/pdb8tj5/pdb
PDB entry 8tj5 coloured by chain, front view.
PDB entry 8tj5 coloured by chain, side view.
PDB entry 8tj5 coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Implications of a multiscale structure of the yeast nuclear pore complex.
Akey CW, Echeverria I, Ouch C, Nudelman I, Shi Y, Wang J, Chait BT, Sali A, Fernandez-Martinez J, Rout MP
Mol Cell 83 3283-3302.e5 (2023)
PMID: 37738963
Related structures: EMD-41300

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero 46-mer (preferred)
PDBe Complex ID:
PDB-CPX-273234 (preferred)
Entry contents:
11 distinct polypeptide molecules
Macromolecules (11 distinct):
Spoke connector Chains: 3, 4, 7, 8, a, b, c, d, e, f, g, h, i, j, k, l, m, n
Molecule details ›
Chains: 3, 4, 7, 8, a, b, c, d, e, f, g, h, i, j, k, l, m, n
Length: 37 amino acids
Theoretical weight: 3.17 KDa
Source organism: Saccharomyces cerevisiae
Nucleoporin NUP170 Chains: 0, Y
Molecule details ›
Chains: 0, Y
Length: 1502 amino acids
Theoretical weight: 169.65 KDa
Source organism: Saccharomyces cerevisiae
Nucleoporin NUP157 Chains: 1, Z
Nucleoporin NSP1 Chains: A, D, G, J
Nucleoporin NUP57 Chains: B, E, H, K
Nucleoporin NUP49/NSP49 Chains: C, F, I, L
Nucleoporin NUP192 Chains: M, O
Nucleoporin NUP188 Chains: N, P
Nucleoporin NIC96 Chains: Q, R, S, T
Nucleoporin NUP53 Chains: U, W
Nucleoporin ASM4 Chains: V, X

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 6.6Å
Relevant EMDB volumes: EMD-41300

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