Function and Biology

KS-AT core of 6-deoxyerythronolide B synthase (DEBS) Module 3 crosslinked with its translocation ACP partner of Module 2

Source organism: Saccharopolyspora erythraea
Biochemical function: acyltransferase activity
Biological process: fatty acid biosynthetic process
Cellular component: not assigned

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00698
Domain description: Acyl transferase domain
Occurring in:
  1. EryAII Erythromycin polyketide synthase modules 3 and 4
The deposited structure of PDB entry 8tko contains 2 copies of Pfam domain PF00698 (Acyl transferase domain) in EryAII. Showing 1 copy in chain B.

PF16197
Domain description: Ketoacyl-synthetase C-terminal extension
Occurring in:
  1. EryAII Erythromycin polyketide synthase modules 3 and 4
The deposited structure of PDB entry 8tko contains 2 copies of Pfam domain PF16197 (Ketoacyl-synthetase C-terminal extension) in EryAII. Showing 1 copy in chain B.

PF02801
Domain description: Beta-ketoacyl synthase, C-terminal domain
Occurring in:
  1. EryAII Erythromycin polyketide synthase modules 3 and 4
The deposited structure of PDB entry 8tko contains 2 copies of Pfam domain PF02801 (Beta-ketoacyl synthase, C-terminal domain) in EryAII. Showing 1 copy in chain B.

PF00109
Domain description: Beta-ketoacyl synthase, N-terminal domain
Occurring in:
  1. EryAII Erythromycin polyketide synthase modules 3 and 4
The deposited structure of PDB entry 8tko contains 2 copies of Pfam domain PF00109 (Beta-ketoacyl synthase, N-terminal domain) in EryAII. Showing 1 copy in chain B.

PF08990
Domain description: Erythronolide synthase docking domain
Occurring in:
  1. EryAII Erythromycin polyketide synthase modules 3 and 4
The deposited structure of PDB entry 8tko contains 2 copies of Pfam domain PF08990 (Erythronolide synthase docking domain) in EryAII. Showing 1 copy in chain B.

PF00550
Domain description: Phosphopantetheine attachment site
Occurring in:
  1. EryAI Erythromycin polyketide synthase modules 1 and 2
The deposited structure of PDB entry 8tko contains 1 copy of Pfam domain PF00550 (Phosphopantetheine attachment site) in EryAI. Showing 1 copy in chain C.