› 8tkt

X-ray diffraction
2.3Å resolution

ZIG-4-INS-6 complex, C-centered monoclinic form

Released:
DOI: 10.2210/pdb8tkt/pdb
PDB entry 8tkt coloured by chain, front view.
PDB entry 8tkt coloured by chain, side view.
PDB entry 8tkt coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways.
Nawrocka WI, Cheng S, Hao B, Rosen MC, Cortés E, Baltrusaitis EE, Aziz Z, Kovács IA, Özkan E
bioRxiv (2024)
PMID: 39026773

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-515458 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Zwei Ig domain protein zig-4 Chains: A, C
Molecule details ›
Chains: A, C
Length: 214 amino acids
Theoretical weight: 23.69 KDa
Source organism: Caenorhabditis elegans
Expression system: Trichoplusia ni
UniProt:
  • Canonical: G5ECB1 (Residues: 42-248; Coverage: 87%)
Gene names: C09C7.1, zig-4
Sequence domains:
Probable insulin-like peptide beta-type 5 Chains: B, D
Molecule details ›
Chains: B, D
Length: 60 amino acids
Theoretical weight: 6.5 KDa
Source organism: Caenorhabditis elegans
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P56174 (Residues: 59-112; Coverage: 58%)
Gene names: ZK84.6, ins-6
Sequence domains: Nematode insulin-related peptide beta type

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: C2
Unit cell:
a: 166.43Å b: 56.654Å c: 73.685Å
α: 90° β: 113.247° γ: 90°
R-values:
R R work R free
0.217 0.215 0.252
Expression system: Trichoplusia ni

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