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8ttz Overview
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8ttz</span> coloured by chain, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Toll-like receptor 7</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>12 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>29 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8ttz_deposited_chain_front_image-800x800.png "PDB entry 8ttz coloured by chain, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8ttz</span> coloured by chain, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Toll-like receptor 7</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>12 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>29 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8ttz_deposited_chain_side_image-800x800.png "PDB entry 8ttz coloured by chain, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8ttz</span> coloured by chain, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Toll-like receptor 7</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>12 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>29 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8ttz_deposited_chain_top_image-800x800.png "PDB entry 8ttz coloured by chain, top view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8ttz</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Toll-like receptor 7</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>12 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>29 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8ttz_deposited_chemically_distinct_molecules_front_image-800x800.png "PDB entry 8ttz coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8ttz</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Toll-like receptor 7</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>12 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>29 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8ttz_deposited_chemically_distinct_molecules_side_image-800x800.png "PDB entry 8ttz coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>The deposited structure of PDB entry <span class='highlight'>8ttz</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Toll-like receptor 7</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>12 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>29 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol</span>;</li> <li class='image_legend_li'>1 copy of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8ttz_deposited_chemically_distinct_molecules_top_image-800x800.png "PDB entry 8ttz coloured by chemically distinct molecules, top view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>8ttz</span> contains 2 copies of <span class='highlight'>(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol</span>. Front view.</div>](https://www.ebi.ac.uk/pdbe/static/entry/8ttz_entity_5_front_image-800x800.png "(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol in PDB entry 8ttz, assembly 1, front view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>8ttz</span> coloured by chemically distinct molecules, front view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Toll-like receptor 7</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>12 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>29 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8ttz_assembly_1_chemically_distinct_molecules_front_image-800x800.png "Homo dimeric assembly 1 of PDB entry 8ttz coloured by chemically distinct molecules, front view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>8ttz</span> coloured by chemically distinct molecules, side view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Toll-like receptor 7</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>12 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>29 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8ttz_assembly_1_chemically_distinct_molecules_side_image-800x800.png "Homo dimeric assembly 1 of PDB entry 8ttz coloured by chemically distinct molecules, side view.")
![<div class='caption-body'>Homo dimeric assembly 1 of PDB entry <span class='highlight'>8ttz</span> coloured by chemically distinct molecules, top view. This structure contains: <ul class='image_legend_ul'><li class='image_legend_li'>2 copies of <span class='highlight'>Toll-like receptor 7</span>;</li> <li class='image_legend_li'>3 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>12 copies of <span class='highlight'>2-acetamido-2-deoxy-beta-D-glucopyranose</span>;</li> <li class='image_legend_li'>29 copies of <span class='highlight'>SULFATE ION</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>(3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol</span>;</li> <li class='image_legend_li'>2 copies of <span class='highlight'>water</span>.</li></ul></div>](https://www.ebi.ac.uk/pdbe/static/entry/8ttz_assembly_1_chemically_distinct_molecules_top_image-800x800.png "Homo dimeric assembly 1 of PDB entry 8ttz coloured by chemically distinct molecules, top view.")