› 8tub

X-ray diffraction
2.4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-245721 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Beta-2-microglobulin Chains: A, B, E, I
Molecule details ›
Chains: A, B, E, I
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
HLA class I histocompatibility antigen, B alpha chain Chains: C, F, G, J
Molecule details ›
Chains: C, F, G, J
Length: 275 amino acids
Theoretical weight: 31.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P01889 (Residues: 25-299; Coverage: 81%)
Gene names: HLA-B, HLAB
Sequence domains:
Non-structural protein 1 Chains: D, H, K, Q
Molecule details ›
Chains: D, H, K, Q
Length: 11 amino acids
Theoretical weight: 1.22 KDa
Source organism: Influenza B virus
Expression system: Not provided
UniProt:
  • Canonical: P12601 (Residues: 196-206; Coverage: 4%)
Gene name: NS

Ligands and Environments

2 bound ligands:
Ligand EDO 6 x EDO
Ligand PEG 1 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P1
Unit cell:
a: 49.211Å b: 90.668Å c: 104.563Å
α: 97.54° β: 93.83° γ: 90.23°
R-values:
R R work R free
0.199 0.197 0.238
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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