Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero hexadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-279216 (preferred)
Entry contents:
13 distinct polypeptide molecules
2 distinct DNA molecules
1 distinct RNA molecule
2 distinct DNA molecules
1 distinct RNA molecule
Macromolecules (16 distinct):
DNA-directed RNA polymerase II subunit RPB1
Chain: A
Molecule details ›
DNA-directed RNA polymerase II subunit RPB2
Chain: B
Molecule details ›
DNA-directed RNA polymerase II subunit RPB3
Chain: C
Molecule details ›
Chain: C
Length: 318 amino acids
Theoretical weight: 35.33 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
Sequence domains:
Length: 318 amino acids
Theoretical weight: 35.33 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
- Canonical:
P16370 (Residues: 1-318; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerase II subunit RPB4
Chain: D
Molecule details ›
Chain: D
Length: 221 amino acids
Theoretical weight: 25.45 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
Sequence domains: RNA polymerase Rpb4
Length: 221 amino acids
Theoretical weight: 25.45 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
- Canonical:
P20433 (Residues: 1-221; Coverage: 100%)
Sequence domains: RNA polymerase Rpb4
DNA-directed RNA polymerases I, II, and III subunit RPABC1
Chain: E
Molecule details ›
DNA-directed RNA polymerases I, II, and III subunit RPABC2
Chain: F
Molecule details ›
Chain: F
Length: 155 amino acids
Theoretical weight: 17.93 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
Sequence domains: RNA polymerase Rpb6
Length: 155 amino acids
Theoretical weight: 17.93 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
- Canonical:
P20435 (Residues: 1-155; Coverage: 100%)
Sequence domains: RNA polymerase Rpb6
DNA-directed RNA polymerase II subunit RPB7
Chain: G
Molecule details ›
Chain: G
Length: 171 amino acids
Theoretical weight: 19.08 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
Sequence domains:
Length: 171 amino acids
Theoretical weight: 19.08 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
- Canonical:
P34087 (Residues: 1-171; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerases I, II, and III subunit RPABC3
Chain: H
Molecule details ›
Chain: H
Length: 146 amino acids
Theoretical weight: 16.53 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
Sequence domains: RNA polymerase Rpb8
Length: 146 amino acids
Theoretical weight: 16.53 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
- Canonical:
P20436 (Residues: 1-146; Coverage: 100%)
Sequence domains: RNA polymerase Rpb8
DNA-directed RNA polymerase II subunit RPB9
Chain: I
Molecule details ›
Chain: I
Length: 122 amino acids
Theoretical weight: 14.31 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
Sequence domains:
Length: 122 amino acids
Theoretical weight: 14.31 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
- Canonical:
P27999 (Residues: 1-122; Coverage: 100%)
Sequence domains:
DNA-directed RNA polymerases I, II, and III subunit RPABC5
Chain: J
Molecule details ›
Chain: J
Length: 70 amino acids
Theoretical weight: 8.29 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
Sequence domains: RNA polymerases N / 8 kDa subunit
Length: 70 amino acids
Theoretical weight: 8.29 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
- Canonical:
P22139 (Residues: 1-70; Coverage: 100%)
Sequence domains: RNA polymerases N / 8 kDa subunit
DNA-directed RNA polymerase II subunit RPB11
Chain: K
Molecule details ›
Chain: K
Length: 120 amino acids
Theoretical weight: 13.63 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
Sequence domains: RNA polymerase Rpb3/Rpb11 dimerisation domain
Length: 120 amino acids
Theoretical weight: 13.63 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
- Canonical:
P38902 (Residues: 1-120; Coverage: 100%)
Sequence domains: RNA polymerase Rpb3/Rpb11 dimerisation domain
DNA-directed RNA polymerases I, II, and III subunit RPABC4
Chain: L
Molecule details ›
Chain: L
Length: 70 amino acids
Theoretical weight: 7.73 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
Sequence domains: DNA directed RNA polymerase, 7 kDa subunit
Length: 70 amino acids
Theoretical weight: 7.73 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
- Canonical:
P40422 (Residues: 1-70; Coverage: 100%)
Sequence domains: DNA directed RNA polymerase, 7 kDa subunit
DNA repair and recombination protein RAD26
Chain: M
Molecule details ›
Chain: M
Length: 434 amino acids
Theoretical weight: 36.95 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
Length: 434 amino acids
Theoretical weight: 36.95 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
DNA (NTS)
Chain: N
Molecule details ›
Chain: N
Length: 47 nucleotides
Theoretical weight: 14.49 KDa
Length: 47 nucleotides
Theoretical weight: 14.49 KDa
DNA (TS)
Chain: T
Molecule details ›
Chain: T
Length: 47 nucleotides
Theoretical weight: 14.27 KDa
Length: 47 nucleotides
Theoretical weight: 14.27 KDa
RNA
Chain: R
Molecule details ›
Chain: R
Length: 17 nucleotides
Theoretical weight: 5.53 KDa
Length: 17 nucleotides
Theoretical weight: 5.53 KDa