› 8twv

Electron Microscopy
3.4Å resolution

ELIC5 with Propylamine in spNW15 nanodiscs with 2:1:1 POPC:POPE:POPG

Released:
DOI: 10.2210/pdb8twv/pdb
PDB entry 8twv coloured by chain, front view.
PDB entry 8twv coloured by chain, side view.
PDB entry 8twv coloured by chain, top view.
Source organism: Dickeya dadantii
Primary publication:
Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.
Dalal V, Arcario MJ, Petroff JT, Tan BK, Dietzen NM, Rau MJ, Fitzpatrick JAJ, Brannigan G, Cheng WWL
OpenAccess logo Nat Commun 15 25 (2024)
PMID: 38167383
Related structures: EMD-41672

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-122692 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 322 amino acids
Theoretical weight: 37.01 KDa
Source organism: Dickeya dadantii
Expression system: Escherichia coli
UniProt:
  • Canonical: E0SJQ4 (Residues: 22-343; Coverage: 100%)
Gene name: Dda3937_00520
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain

Ligands and Environments

1 bound ligand:
Ligand 3CN 5 x 3CN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-41672
Expression system: Escherichia coli

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