8tyc

Electron Microscopy
3.3Å resolution

Lassa GPC (strain Josiah) bound to rabbit polyclonal base-targeting antibody Base-1

Released:
Entry authors: Perrett HR, Brouwer PJM, Ward AB
Related structures: EMD-41713

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-251296 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (9 distinct):
Glycoprotein G1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 259 amino acids
Theoretical weight: 29.01 KDa
Source organism: Lassa virus Josiah
Expression system: Homo sapiens
UniProt:
  • Canonical: P08669 (Residues: 1-259; Coverage: 53%)
Gene names: GP-C, GPC
Sequence domains: Arenavirus glycoprotein
Polyclonal antibody Base-1 heavy chain Chain: H
Molecule details ›
Chain: H
Length: 108 amino acids
Theoretical weight: 9.21 KDa
Source organism: Oryctolagus cuniculus
Polyclonal antibody Base-1 light chain Chain: L
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Glycoprotein G2 Chains: a, b, c

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-41713
Expression system: Homo sapiens