› 8tzv

Electron Microscopy
2.8Å resolution

Apo form of human ATE1

Released:
DOI: 10.2210/pdb8tzv/pdb
PDB entry 8tzv coloured by chain, front view.
PDB entry 8tzv coloured by chain, side view.
PDB entry 8tzv coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Oligomerization and a distinct tRNA-binding loop are important regulators of human arginyl-transferase function.
Lan X, Huang W, Kim SB, Fu D, Abeywansha T, Lou J, Balamurugan U, Kwon YT, Ji CH, Taylor DJ, Zhang Y
Nat Commun 15 6350 (2024)
PMID: 39068213
Related structures: EMD-41770

Function and Biology Details

Reaction catalysed: 
L-arginyl-tRNA(Arg) + [protein] = tRNA(Arg) + L-arginyl-[protein]
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-271924 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arginyl-tRNA--protein transferase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 519 amino acids
Theoretical weight: 59.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: O95260 (Residues: 2-518; Coverage: 100%)
  • Best match: O95260-2 (Residues: 2-518)
Gene name: ATE1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.8Å
Relevant EMDB volumes: EMD-41770
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

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