› 8u31

X-ray diffraction
2.73Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-246086 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Programmed cell death protein 1 Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 15.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15116 (Residues: 25-146; Coverage: 46%)
Gene names: PD1, PDCD1
Sequence domains: Immunoglobulin V-set domain
Fab light chain Chain: B
Molecule details ›
Chain: B
Length: 218 amino acids
Theoretical weight: 23.51 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Fab heavy chain Chain: C
Molecule details ›
Chain: C
Length: 229 amino acids
Theoretical weight: 24.03 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 44.069Å b: 104.069Å c: 143.43Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.199 0.238
Expression systems:
  • Escherichia coli
  • Cricetulus griseus

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