8u54

Electron Microscopy
2.65Å resolution

The mTORC1 cholesterol sensor LYCHOS (GPR155)

Released:

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-275014 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysosomal cholesterol signaling protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 890 amino acids
Theoretical weight: 99.28 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q7Z3F1 (Residues: 1-870; Coverage: 100%)
Gene names: GPR155, PGR22
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.65Å
Relevant EMDB volumes: EMD-41912
Expression system: Homo sapiens