› 8u5c

Electron Microscopy
2.68Å resolution

The mTORC1 cholesterol sensor LYCHOS (GPR155) with cholesterol

Released:
DOI: 10.2210/pdb8u5c/pdb
PDB entry 8u5c coloured by chain, front view.
PDB entry 8u5c coloured by chain, side view.
PDB entry 8u5c coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Bayly-Jones C, Lupton CJ, Ellisdon AM
Related structures: EMD-41916

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-251558 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysosomal cholesterol signaling protein Chains: E, F
Molecule details ›
Chains: E, F
Length: 890 amino acids
Theoretical weight: 99.17 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q7Z3F1 (Residues: 1-870; Coverage: 100%)
Gene names: GPR155, PGR22
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand Y01 4 x Y01
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.68Å
Relevant EMDB volumes: EMD-41916
Expression system: Homo sapiens

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