› 8u5d

X-ray diffraction
1.6Å resolution

Crystal Structure of C-terminal domain of Clostridium perfringens Enterotoxin in Space Group P 41 21 2

Released:
DOI: 10.2210/pdb8u5d/pdb
PDB entry 8u5d coloured by chain, front view.
PDB entry 8u5d coloured by chain, side view.
PDB entry 8u5d coloured by chain, top view.
Source organism: Clostridium perfringens
Primary publication:
Structural Basis of Clostridium perfringens Enterotoxin Activation and Oligomerization by Trypsin.
Ogbu CP, Kapoor S, Vecchio AJ
OpenAccess logo Toxins (Basel) 15 (2023)
PMID: 37999500

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-272050 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat-labile enterotoxin B chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 145 amino acids
Theoretical weight: 15.68 KDa
Source organism: Clostridium perfringens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P01558 (Residues: 194-319; Coverage: 40%)
Gene name: cpe

Ligands and Environments

3 bound ligands:
Ligand ACT 11 x ACT
Ligand GOL 18 x GOL
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P41212
Unit cell:
a: 65.12Å b: 65.12Å c: 130.77Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.196 0.223
Expression system: Spodoptera frugiperda

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