› 8u7e

X-ray diffraction
2.63Å resolution

Function and Biology Details

Reaction catalysed: 
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186265 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin-associated and SH3 domain-containing protein B Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 287 amino acids
Theoretical weight: 32.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8TF42 (Residues: 380-649; Coverage: 42%)
Gene names: KIAA1959, STS1, UBASH3B
Sequence domains: Histidine phosphatase superfamily (branch 1)

Ligands and Environments

1 bound ligand:
Ligand VXE 3 x VXE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 82.777Å b: 122.701Å c: 99.945Å
α: 90° β: 112.62° γ: 90°
R-values:
R R work R free
0.219 0.215 0.298
Expression system: Escherichia coli

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