8ubv

Electron Microscopy
4.1Å resolution

Cryo-EM structure of dimeric FBXL17-BACH1BTB E3 ubiquitin ligase complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-280785 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
F-box/LRR-repeat protein 17 Chains: B, H
Molecule details ›
Chains: B, H
Length: 392 amino acids
Theoretical weight: 44.51 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9UF56 (Residues: 310-701; Coverage: 56%)
Gene names: FBL17, FBX13, FBXL17, FBXO13
Sequence domains:
Transcription regulator protein BACH1 Chains: C, I
Molecule details ›
Chains: C, I
Length: 122 amino acids
Theoretical weight: 13.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O14867 (Residues: 7-128; Coverage: 17%)
Gene name: BACH1
Sequence domains: BTB/POZ domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.1Å
Relevant EMDB volumes: EMD-42106
Expression systems:
  • Trichoplusia ni
  • Escherichia coli BL21