8ucc

X-ray diffraction
1.8Å resolution

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-192669 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interleukin-1 receptor-associated kinase 4 Chain: A
Molecule details ›
Chain: A
Length: 307 amino acids
Theoretical weight: 34.58 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9NWZ3 (Residues: 154-460; Coverage: 67%)
Gene name: IRAK4
Sequence domains: Protein tyrosine and serine/threonine kinase
Interleukin-1 receptor-associated kinase 4 Chain: B
Molecule details ›
Chain: B
Length: 307 amino acids
Theoretical weight: 34.5 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9NWZ3 (Residues: 154-460; Coverage: 67%)
Gene name: IRAK4
Sequence domains: Protein tyrosine and serine/threonine kinase

Ligands and Environments

1 bound ligand:
2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: I222
Unit cell:
a: 88.632Å b: 118.025Å c: 140.017Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.208 0.24
Expression system: Trichoplusia ni