Function and Biology

In-situ structure of typeA supercomplex with lipids in respiratory chain (composite)

Source organism: Sus scrofa
Biochemical function: metal ion binding
Biological process: proton transmembrane transport
Cellular component: mitochondrion

EC 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating)

Reaction catalysed:
NADH + ubiquinone + 5 H(+)(Side 1) = NAD(+) + ubiquinol + 4 H(+)(Side 2)
Systematic name:
NADH:ubiquinone oxidoreductase
Alternative Name(s):
  • Coenzyme Q reductase
  • Complex 1 dehydrogenase
  • Complex I (NADH:Q1 oxidoreductase)
  • Complex I (electron transport chain)
  • Complex I (mitochondrial electron transport)
  • DPNH-coenzyme Q reductase
  • DPNH-ubiquinone reductase
  • Dihydronicotinamide adenine dinucleotide-coenzyme Q reductase
  • Electron transfer complex I
  • Mitochondrial electron transport complex 1
  • Mitochondrial electron transport complex I
  • NADH coenzyme Q1 reductase
  • NADH dehydrogenase (ubiquinone)
  • NADH-CoQ oxidoreductase
  • NADH-CoQ reductase
  • NADH-Q6 oxidoreductase
  • NADH-coenzyme Q oxidoreductase
  • NADH-coenzyme Q reductase
  • NADH-ubiquinone oxidoreductase
  • NADH-ubiquinone reductase
  • NADH-ubiquinone-1 reductase
  • NADH:ubiquinone oxidoreductase complex
  • Reduced nicotinamide adenine dinucleotide-coenzyme Q reductase
  • Type 1 dehydrogenase
  • Ubiquinone reductase

EC 7.1.1.8: Quinol--cytochrome-c reductase

Reaction catalysed:
Quinol + 2 ferricytochrome c(Side 2) = quinone + 2 ferrocytochrome c(Side 2) + 2 H(+)(Side 2)
Systematic name:
Quinol:ferricytochrome-c oxidoreductase
Alternative Name(s):
  • CoQH(2)--cytochrome c oxidoreductase
  • Coenzyme Q--cytochrome c reductase
  • Coenzyme QH(2)--cytochrome c reductase
  • Complex III (mitochondrial electron transport)
  • Cytochrome bc1 complex
  • Dihydrocoenzyme Q--cytochrome c reductase
  • Mitochondrial electron transport complex III
  • QH(2):cytochrome c oxidoreductase
  • Reduced coenzyme Q-cytochrome c reductase
  • Reduced ubiquinone--cytochrome c oxidoreductase
  • Reduced ubiquinone--cytochrome c reductase, complex III (mitochondrial electron transport)
  • Ubihydroquinol:cytochrome c oxidoreductase
  • Ubiquinol--cytochrome c oxidoreductase
  • Ubiquinol--cytochrome c-2 oxidoreductase
  • Ubiquinol--cytochrome c1 oxidoreductase
  • Ubiquinol--cytochrome c2 reductase
  • Ubiquinol--cytochrome-c reductase
  • Ubiquinol:ferricytochrome-c oxidoreductase
  • Ubiquinone--cytochrome b-c(1) oxidoreductase
  • Ubiquinone--cytochrome c oxidoreductase
  • Ubiquinone--cytochrome-c oxidoreductase
  • Ubiquinone-cytochrome c reductase

EC 7.1.1.9: Cytochrome-c oxidase

Reaction catalysed:
4 ferrocytochrome c + O(2) + 8 H(+)(Side 1) = 4 ferricytochrome c + 4 H(2)O(Side 2)
Systematic name:
Ferrocytochrome-c:oxygen oxidoreductase
Alternative Name(s):
  • Complex IV (mitochondrial electron transport)
  • Cytochrome a3
  • Cytochrome aa3
  • Cytochrome ba(3)
  • Cytochrome bb3
  • Cytochrome caa(3)
  • Cytochrome cbb(3)
  • Cytochrome oxidase
  • Ferrocytochrome c oxidase
  • Indophenol oxidase
  • Indophenolase
  • NADH cytochrome c oxidase
  • Warburg's respiratory enzyme

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00355
Domain description: Rieske [2Fe-2S] domain
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
The deposited structure of PDB entry 8ugh contains 4 copies of Pfam domain PF00355 (Rieske [2Fe-2S] domain) in Cytochrome b-c1 complex subunit Rieske, mitochondrial. Showing 1 copy in chain XA [auth 3E].

PF02921
Domain description: Ubiquinol cytochrome reductase transmembrane region
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
The deposited structure of PDB entry 8ugh contains 4 copies of Pfam domain PF02921 (Ubiquinol cytochrome reductase transmembrane region) in Cytochrome b-c1 complex subunit Rieske, mitochondrial. Showing 1 copy in chain XA [auth 3E].

PF09165
Domain description: Ubiquinol-cytochrome c reductase 8 kDa, N-terminal
Occurring in:
  1. Cytochrome b-c1 complex subunit Rieske, mitochondrial
The deposited structure of PDB entry 8ugh contains 4 copies of Pfam domain PF09165 (Ubiquinol-cytochrome c reductase 8 kDa, N-terminal) in Cytochrome b-c1 complex subunit Rieske, mitochondrial. Showing 1 copy in chain XA [auth 3E] (this domain is out of the observed residue ranges!).

PF05193
Domain description: Peptidase M16 inactive domain
Occurring in:
  1. Cytochrome b-c1 complex subunit 1, mitochondrial
  2. Cytochrome b-c1 complex subunit 2, mitochondrial
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF05193 (Peptidase M16 inactive domain) in Cytochrome b-c1 complex subunit 1, mitochondrial. Showing 1 copy in chain DB [auth 3N].
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF05193 (Peptidase M16 inactive domain) in Cytochrome b-c1 complex subunit 2, mitochondrial. Showing 1 copy in chain UA [auth 3B].

PF00675
Domain description: Insulinase (Peptidase family M16)
Occurring in:
  1. Cytochrome b-c1 complex subunit 1, mitochondrial
  2. Cytochrome b-c1 complex subunit 2, mitochondrial
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF00675 (Insulinase (Peptidase family M16)) in Cytochrome b-c1 complex subunit 1, mitochondrial. Showing 1 copy in chain DB [auth 3N].
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF00675 (Insulinase (Peptidase family M16)) in Cytochrome b-c1 complex subunit 2, mitochondrial. Showing 1 copy in chain UA [auth 3B].

PF00361
Domain description: Proton-conducting membrane transporter
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
  2. NADH-ubiquinone oxidoreductase chain 4
  3. NADH-ubiquinone oxidoreductase chain 2
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00361 (Proton-conducting membrane transporter) in NADH-ubiquinone oxidoreductase chain 5. Showing 1 copy in chain L [auth 1L].
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00361 (Proton-conducting membrane transporter) in NADH-ubiquinone oxidoreductase chain 4. Showing 1 copy in chain M [auth 1M].
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00361 (Proton-conducting membrane transporter) in NADH-ubiquinone oxidoreductase chain 2. Showing 1 copy in chain N [auth 1N].

PF08997
Domain description: Ubiquinol-cytochrome C reductase complex, 6.4kD protein
Occurring in:
  1. Cytochrome b-c1 complex subunit 10
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF08997 (Ubiquinol-cytochrome C reductase complex, 6.4kD protein) in Cytochrome b-c1 complex subunit 10. Showing 1 copy in chain NB [auth 3X].

PF05365
Domain description: Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like
Occurring in:
  1. Complex III subunit 9
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF05365 (Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like) in Complex III subunit 9. Showing 1 copy in chain CB [auth 3J].

PF02320
Domain description: Ubiquinol-cytochrome C reductase hinge protein
Occurring in:
  1. Cytochrome b-c1 complex subunit 6
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF02320 (Ubiquinol-cytochrome C reductase hinge protein) in Cytochrome b-c1 complex subunit 6. Showing 1 copy in chain AB [auth 3H].

PF02939
Domain description: UcrQ family
Occurring in:
  1. Cytochrome b-c1 complex subunit 8
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF02939 (UcrQ family) in Cytochrome b-c1 complex subunit 8. Showing 1 copy in chain ZA [auth 3G].

PF02271
Domain description: Ubiquinol-cytochrome C reductase complex 14kD subunit
Occurring in:
  1. Cytochrome b-c1 complex subunit 7
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF02271 (Ubiquinol-cytochrome C reductase complex 14kD subunit) in Cytochrome b-c1 complex subunit 7. Showing 1 copy in chain YA [auth 3F].

PF02167
Domain description: Cytochrome C1 family
Occurring in:
  1. Cytochrome c domain-containing protein
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF02167 (Cytochrome C1 family) in Cytochrome c domain-containing protein. Showing 1 copy in chain GB [auth 3Q].

PF00032
Domain description: Cytochrome b(C-terminal)/b6/petD
Occurring in:
  1. Cytochrome b
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF00032 (Cytochrome b(C-terminal)/b6/petD) in Cytochrome b. Showing 1 copy in chain VA [auth 3C].

PF00033
Domain description: Cytochrome b/b6/petB
Occurring in:
  1. Cytochrome b
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF00033 (Cytochrome b/b6/petB) in Cytochrome b. Showing 1 copy in chain VA [auth 3C].

PF00550
Domain description: Phosphopantetheine attachment site
Occurring in:
  1. Acyl carrier protein
The deposited structure of PDB entry 8ugh contains 2 copies of Pfam domain PF00550 (Phosphopantetheine attachment site) in Acyl carrier protein. Showing 1 copy in chain U [auth 1U].

PF06522
Domain description: NADH-ubiquinone reductase complex 1 MLRQ subunit
Occurring in:
  1. Mitochondrial NDUFA4
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF06522 (NADH-ubiquinone reductase complex 1 MLRQ subunit) in Mitochondrial NDUFA4. Showing 1 copy in chain CC [auth 4N].

PF02285
Domain description: Cytochrome oxidase c subunit VIII
Occurring in:
  1. Cytochrome c oxidase subunit 8
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF02285 (Cytochrome oxidase c subunit VIII) in Cytochrome c oxidase subunit 8. Showing 1 copy in chain BC [auth 4M].

PF02935
Domain description: Cytochrome c oxidase subunit VIIc
Occurring in:
  1. Cytochrome c oxidase subunit 7C, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF02935 (Cytochrome c oxidase subunit VIIc) in Cytochrome c oxidase subunit 7C, mitochondrial. Showing 1 copy in chain AC [auth 4L].

PF05392
Domain description: Cytochrome C oxidase chain VIIB
Occurring in:
  1. Cytochrome c oxidase subunit 7B, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF05392 (Cytochrome C oxidase chain VIIB) in Cytochrome c oxidase subunit 7B, mitochondrial. Showing 1 copy in chain ZB [auth 4K].

PF02238
Domain description: Cytochrome c oxidase subunit VII
Occurring in:
  1. Cytochrome c oxidase subunit 7A1, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF02238 (Cytochrome c oxidase subunit VII) in Cytochrome c oxidase subunit 7A1, mitochondrial. Showing 1 copy in chain YB [auth 4J].

PF02937
Domain description: Cytochrome c oxidase subunit VIc
Occurring in:
  1. Cytochrome c oxidase subunit 6C
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF02937 (Cytochrome c oxidase subunit VIc) in Cytochrome c oxidase subunit 6C. Showing 1 copy in chain XB [auth 4I].

PF02297
Domain description: Cytochrome oxidase c subunit VIb
Occurring in:
  1. Cytochrome c oxidase subunit
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF02297 (Cytochrome oxidase c subunit VIb) in Cytochrome c oxidase subunit. Showing 1 copy in chain WB [auth 4H].

PF02046
Domain description: Cytochrome c oxidase subunit VIa
Occurring in:
  1. Cytochrome c oxidase subunit
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF02046 (Cytochrome c oxidase subunit VIa) in Cytochrome c oxidase subunit. Showing 1 copy in chain VB [auth 4G].

PF01215
Domain description: Cytochrome c oxidase subunit Vb
Occurring in:
  1. Cytochrome c oxidase subunit 5B, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF01215 (Cytochrome c oxidase subunit Vb) in Cytochrome c oxidase subunit 5B, mitochondrial. Showing 1 copy in chain UB [auth 4F].

PF02284
Domain description: Cytochrome c oxidase subunit Va
Occurring in:
  1. Cytochrome c oxidase subunit 5A, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF02284 (Cytochrome c oxidase subunit Va) in Cytochrome c oxidase subunit 5A, mitochondrial. Showing 1 copy in chain TB [auth 4E].

PF02936
Domain description: Cytochrome c oxidase subunit IV
Occurring in:
  1. Cytochrome c oxidase subunit 4
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF02936 (Cytochrome c oxidase subunit IV) in Cytochrome c oxidase subunit 4. Showing 1 copy in chain SB [auth 4D].

PF00510
Domain description: Cytochrome c oxidase subunit III
Occurring in:
  1. Cytochrome c oxidase subunit 3
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00510 (Cytochrome c oxidase subunit III) in Cytochrome c oxidase subunit 3. Showing 1 copy in chain RB [auth 4C].

PF00116
Domain description: Cytochrome C oxidase subunit II, periplasmic domain
Occurring in:
  1. Cytochrome c oxidase subunit 2
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00116 (Cytochrome C oxidase subunit II, periplasmic domain) in Cytochrome c oxidase subunit 2. Showing 1 copy in chain QB [auth 4B].

PF02790
Domain description: Cytochrome C oxidase subunit II, transmembrane domain
Occurring in:
  1. Cytochrome c oxidase subunit 2
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF02790 (Cytochrome C oxidase subunit II, transmembrane domain) in Cytochrome c oxidase subunit 2. Showing 1 copy in chain QB [auth 4B].

PF00115
Domain description: Cytochrome C and Quinol oxidase polypeptide I
Occurring in:
  1. Cytochrome c oxidase subunit 1
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00115 (Cytochrome C and Quinol oxidase polypeptide I) in Cytochrome c oxidase subunit 1. Showing 1 copy in chain PB [auth 4A].

PF15880
Domain description: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Occurring in:
  1. NADH:ubiquinone oxidoreductase subunit V3
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF15880 (NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial) in NADH:ubiquinone oxidoreductase subunit V3. Showing 1 copy in chain SA [auth 1s].

PF07347
Domain description: NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF07347 (NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. Showing 1 copy in chain RA [auth 1r].

PF05071
Domain description: NADH ubiquinone oxidoreductase subunit NDUFA12
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF05071 (NADH ubiquinone oxidoreductase subunit NDUFA12) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12. Showing 1 copy in chain QA [auth 1q].

PF10249
Domain description: NADH-ubiquinone oxidoreductase subunit 10
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF10249 (NADH-ubiquinone oxidoreductase subunit 10) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10. Showing 1 copy in chain PA [auth 1p].

PF05676
Domain description: NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF05676 (NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. Showing 1 copy in chain OA [auth 1o].

PF07225
Domain description: NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF07225 (NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. Showing 1 copy in chain MA [auth 1m].

PF05821
Domain description: NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF05821 (NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial. Showing 1 copy in chain LA [auth 1l].

PF08122
Domain description: NADH-ubiquinone oxidoreductase B12 subunit family
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF08122 (NADH-ubiquinone oxidoreductase B12 subunit family) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. Showing 1 copy in chain KA [auth 1k].

PF14813
Domain description: NADH dehydrogenase 1 beta subcomplex subunit 2
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF14813 (NADH dehydrogenase 1 beta subcomplex subunit 2) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial. Showing 1 copy in chain JA [auth 1j].

PF09782
Domain description: NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF09782 (NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6. Showing 1 copy in chain IA [auth 1i].

PF09781
Domain description: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF09781 (NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial. Showing 1 copy in chain HA [auth 1h].

PF10183
Domain description: ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF10183 (ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial. Showing 1 copy in chain GA [auth 1g].

PF08040
Domain description: MNLL subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF08040 (MNLL subunit) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1. Showing 1 copy in chain FA [auth 1f].

PF10200
Domain description: NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 5
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF10200 (NADH:ubiquinone oxidoreductase, NDUFS5-15kDa) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 5. Showing 1 copy in chain EA [auth 1e].

PF06374
Domain description: NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 subunit C2
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF06374 (NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)) in NADH dehydrogenase [ubiquinone] 1 subunit C2. Showing 1 copy in chain DA [auth 1d].

PF15088
Domain description: NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF15088 (NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial) in NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial. Showing 1 copy in chain CA [auth 1c].

PF14987
Domain description: NADH dehydrogenase 1 alpha subcomplex subunit 3
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF14987 (NADH dehydrogenase 1 alpha subcomplex subunit 3) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3. Showing 1 copy in chain BA [auth 1b].

PF15879
Domain description: NADH-ubiquinone oxidoreductase MWFE subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF15879 (NADH-ubiquinone oxidoreductase MWFE subunit) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1. Showing 1 copy in chain AA [auth 1a].

PF06212
Domain description: GRIM-19 protein
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF06212 (GRIM-19 protein) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. Showing 1 copy in chain Z [auth 1Z].

PF02466
Domain description: Tim17/Tim22/Tim23/Pmp24 family
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF02466 (Tim17/Tim22/Tim23/Pmp24 family) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11. Showing 1 copy in chain Y [auth 1Y].

PF06747
Domain description: CHCH domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF06747 (CHCH domain) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8. Showing 1 copy in chain X [auth 1X].

PF04716
Domain description: ETC complex I subunit conserved region
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF04716 (ETC complex I subunit conserved region) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. Showing 1 copy in chain V [auth 1V].

PF05047
Domain description: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF05047 (Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2. Showing 1 copy in chain S [auth 1S].

PF10276
Domain description: Zinc-finger domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF10276 (Zinc-finger domain) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial. Showing 1 copy in chain R [auth 1R].

PF04800
Domain description: NADH dehydrogenase ubiquinone Fe-S protein 4
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF04800 (NADH dehydrogenase ubiquinone Fe-S protein 4) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. Showing 1 copy in chain Q [auth 1Q].

PF01370
Domain description: NAD dependent epimerase/dehydratase family
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF01370 (NAD dependent epimerase/dehydratase family) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial. Showing 1 copy in chain P [auth 1P].

PF01712
Domain description: Deoxynucleoside kinase
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF01712 (Deoxynucleoside kinase) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial. Showing 1 copy in chain O [auth 1O].

PF06444
Domain description: NADH dehydrogenase subunit 2 C-terminus
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 2
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF06444 (NADH dehydrogenase subunit 2 C-terminus) in NADH-ubiquinone oxidoreductase chain 2. Showing 1 copy in chain N [auth 1N].

PF01059
Domain description: NADH-ubiquinone oxidoreductase chain 4, amino terminus
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF01059 (NADH-ubiquinone oxidoreductase chain 4, amino terminus) in NADH-ubiquinone oxidoreductase chain 4. Showing 1 copy in chain M [auth 1M].

PF06455
Domain description: NADH dehydrogenase subunit 5 C-terminus
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF06455 (NADH dehydrogenase subunit 5 C-terminus) in NADH-ubiquinone oxidoreductase chain 5. Showing 1 copy in chain L [auth 1L].

PF00662
Domain description: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00662 (NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus) in NADH-ubiquinone oxidoreductase chain 5. Showing 1 copy in chain L [auth 1L].

PF00420
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4L
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00420 (NADH-ubiquinone/plastoquinone oxidoreductase chain 4L) in NADH-ubiquinone oxidoreductase chain 4L. Showing 1 copy in chain K [auth 1K].

PF00499
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase chain 6
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 6
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00499 (NADH-ubiquinone/plastoquinone oxidoreductase chain 6) in NADH-ubiquinone oxidoreductase chain 6. Showing 1 copy in chain J [auth 1J].

PF12838
Domain description: 4Fe-4S dicluster domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF12838 (4Fe-4S dicluster domain) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial. Showing 1 copy in chain I [auth 1I].

PF00146
Domain description: NADH dehydrogenase
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 1
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00146 (NADH dehydrogenase) in NADH-ubiquinone oxidoreductase chain 1. Showing 1 copy in chain H [auth 1H].

PF09326
Domain description: NADH-ubiquinone oxidoreductase subunit G, C-terminal
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF09326 (NADH-ubiquinone oxidoreductase subunit G, C-terminal) in NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial. Showing 1 copy in chain G [auth 1G].

PF00384
Domain description: Molybdopterin oxidoreductase
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00384 (Molybdopterin oxidoreductase) in NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial. Showing 1 copy in chain G [auth 1G].

PF22151
Domain description: NADH-ubiquinone oxidoreductase NDSU1/NuoG-like, 4Fe-4S domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF22151 (NADH-ubiquinone oxidoreductase NDSU1/NuoG-like, 4Fe-4S domain) in NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial. Showing 1 copy in chain G [auth 1G].

PF22117
Domain description: NADH-quinone oxidoreductase subunit 3, ferredoxin-like domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF22117 (NADH-quinone oxidoreductase subunit 3, ferredoxin-like domain) in NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial. Showing 1 copy in chain G [auth 1G].

PF10588
Domain description: NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF10588 (NADH-ubiquinone oxidoreductase-G iron-sulfur binding region) in NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial. Showing 1 copy in chain G [auth 1G].

PF13510
Domain description: 2Fe-2S iron-sulfur cluster binding domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF13510 (2Fe-2S iron-sulfur cluster binding domain) in NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial. Showing 1 copy in chain G [auth 1G].

PF10589
Domain description: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF10589 (NADH-ubiquinone oxidoreductase-F iron-sulfur binding region) in NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial. Showing 1 copy in chain F [auth 1F].

PF22461
Domain description: SLBB domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF22461 (SLBB domain) in NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial. Showing 1 copy in chain F [auth 1F].

PF01512
Domain description: Respiratory-chain NADH dehydrogenase 51 Kd subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF01512 (Respiratory-chain NADH dehydrogenase 51 Kd subunit) in NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial. Showing 1 copy in chain F [auth 1F].

PF01257
Domain description: Thioredoxin-like [2Fe-2S] ferredoxin
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF01257 (Thioredoxin-like [2Fe-2S] ferredoxin) in NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial. Showing 1 copy in chain E [auth 1E].

PF00346
Domain description: Respiratory-chain NADH dehydrogenase, 49 Kd subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00346 (Respiratory-chain NADH dehydrogenase, 49 Kd subunit) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial. Showing 1 copy in chain D [auth 1D].

PF00329
Domain description: Respiratory-chain NADH dehydrogenase, 30 Kd subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00329 (Respiratory-chain NADH dehydrogenase, 30 Kd subunit) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial. Showing 1 copy in chain C [auth 1C].

PF01058
Domain description: NADH ubiquinone oxidoreductase, 20 Kd subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF01058 (NADH ubiquinone oxidoreductase, 20 Kd subunit) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial. Showing 1 copy in chain B [auth 1B].

PF00507
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 3
The deposited structure of PDB entry 8ugh contains 1 copy of Pfam domain PF00507 (NADH-ubiquinone/plastoquinone oxidoreductase, chain 3) in NADH-ubiquinone oxidoreductase chain 3. Showing 1 copy in chain A [auth 1A].