Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 21-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-281124 (preferred)
Entry contents:
18 distinct polypeptide molecules
2 distinct DNA molecules
1 distinct RNA molecule
2 distinct DNA molecules
1 distinct RNA molecule
Macromolecules (21 distinct):
Negative elongation factor E
Chain: X
Molecule details ›
Chain: X
Length: 380 amino acids
Theoretical weight: 43.32 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 380 amino acids
Theoretical weight: 43.32 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Transcription elongation factor SPT5
Chain: Z
Molecule details ›
Chain: Z
Length: 1087 amino acids
Theoretical weight: 121.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 1087 amino acids
Theoretical weight: 121.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Negative elongation factor C/D
Chain: W
Molecule details ›
Chain: W
Length: 590 amino acids
Theoretical weight: 66.32 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 590 amino acids
Theoretical weight: 66.32 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Negative elongation factor B
Chain: V
Molecule details ›
Chain: V
Length: 580 amino acids
Theoretical weight: 65.78 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 580 amino acids
Theoretical weight: 65.78 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
DNA-directed RNA polymerase subunit
Chain: A
DNA-directed RNA polymerase subunit beta
Chain: B
DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
Chain: C
RNA polymerase Rpb4/RPC9 core domain-containing protein
Chain: D
DNA-directed RNA polymerase II subunit E
Chain: E
DNA-directed RNA polymerases I, II, and III subunit RPABC2
Chain: F
DNA-directed RNA polymerase subunit
Chain: G
DNA-directed RNA polymerases I, II, and III subunit RPABC3
Chain: H
DNA-directed RNA polymerase II subunit RPB9
Chain: I
DNA-directed RNA polymerases I, II, and III subunit RPABC5
Chain: J
DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein
Chain: K
RNA polymerase II, I and III subunit K
Chain: L
Negative elongation factor A
Chain: U
Molecule details ›
Chain: U
Length: 527 amino acids
Theoretical weight: 55.69 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 527 amino acids
Theoretical weight: 55.69 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Transcription elongation factor SPT4
Chain: Y
Molecule details ›
Chain: Y
Length: 117 amino acids
Theoretical weight: 13.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 117 amino acids
Theoretical weight: 13.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Non-template DNA
Chain: N
Molecule details ›
Chain: N
Length: 50 nucleotides
Theoretical weight: 15.41 KDa
Source organism: synthetic construct
Expression system: Not provided
Length: 50 nucleotides
Theoretical weight: 15.41 KDa
Source organism: synthetic construct
Expression system: Not provided
Template DNA
Chain: T
Molecule details ›
Chain: T
Length: 50 nucleotides
Theoretical weight: 15.4 KDa
Source organism: synthetic construct
Expression system: Not provided
Length: 50 nucleotides
Theoretical weight: 15.4 KDa
Source organism: synthetic construct
Expression system: Not provided
RNA
Chain: P
Molecule details ›
Chain: P
Length: 22 nucleotides
Theoretical weight: 6.97 KDa
Source organism: synthetic construct
Expression system: Not provided
Length: 22 nucleotides
Theoretical weight: 6.97 KDa
Source organism: synthetic construct
Expression system: Not provided