› 8uip

Electron Microscopy
4.3Å resolution

Cryo-EM Structure of Human Ninjurin1 curved oligomer

Released:
DOI: 10.2210/pdb8uip/pdb
PDB entry 8uip coloured by chain, front view.
PDB entry 8uip coloured by chain, side view.
PDB entry 8uip coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks.
David L, Borges JP, Hollingsworth LR, Volchuk A, Jansen I, Garlick E, Steinberg BE, Wu H
Cell (2024)
PMID: 38614101
Related structures: EMD-42301

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-275251 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ninjurin-1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 152 amino acids
Theoretical weight: 16.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia phage EcSzw_1
UniProt:
  • Canonical: Q92982 (Residues: 1-152; Coverage: 100%)
Gene name: NINJ1
Sequence domains: Ninjurin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.3Å
Relevant EMDB volumes: EMD-42301
Expression system: Escherichia phage EcSzw_1

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