![1-{(4M)-4-[2-{[1-(cyclopropanesulfonyl)piperidin-4-yl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]-1H-pyrazol-1-yl}-2-methylpropan-2-ol in PDB entry 8uv0, assembly 1, side view.](https://www.ebi.ac.uk/pdbe/static/entry/8uv0_entity_2_side_image-200x200.png "Monomeric assembly 1 of PDB entry <span class='highlight'>8uv0</span> contains 1 copy of <span class='highlight'>1-{(4M)-4-[2-{[1-(cyclopropanesulfonyl)piperidin-4-yl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]-1H-pyrazol-1-yl}-2-methylpropan-2-ol</span>. Side view.")
![1-{(4M)-4-[2-{[1-(cyclopropanesulfonyl)piperidin-4-yl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]-1H-pyrazol-1-yl}-2-methylpropan-2-ol in PDB entry 8uv0, assembly 1, top view.](https://www.ebi.ac.uk/pdbe/static/entry/8uv0_entity_2_top_image-200x200.png "Monomeric assembly 1 of PDB entry <span class='highlight'>8uv0</span> contains 1 copy of <span class='highlight'>1-{(4M)-4-[2-{[1-(cyclopropanesulfonyl)piperidin-4-yl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]-1H-pyrazol-1-yl}-2-methylpropan-2-ol</span>. Top view.")
Environment details NEW
XKU 301 bound to chain A
The above 2D and 3D (Mol*) views of ligand interactions use quaternary structure derived from the PDB entry.
Please note:
Please note:
- Some chain IDs in the tooltip are followed by a number in square brackets. This number corresponds to the operation ID (mmCIF ‘oper_expression’) used to transform the chain.
- The structure seen in Mol* (3D view) was protonated using ChimeraX.
- Interactions were calculated using Arpeggio (see details for interaction types).
- The colour scheme used is consistent with Clustal X.