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Electron Microscopy
3.5Å resolution

Consensus olfactory receptor consOR4 bound to 2-methylthiazoline and in complex with mini-Gs trimeric protein

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-281639 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
consOR4 Chain: A
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 36.26 KDa
Source organism: synthetic construct
Expression system: Homo sapiens
Nanobody 35 Chain: N
Molecule details ›
Chain: N
Length: 145 amino acids
Theoretical weight: 15.93 KDa
Source organism: Lama glama
Expression system: Escherichia coli
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Chain: X
Molecule details ›
Chain: X
Length: 261 amino acids
Theoretical weight: 30.14 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: Y
Molecule details ›
Chain: Y
Length: 370 amino acids
Theoretical weight: 40.79 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: Z
Molecule details ›
Chain: Z
Length: 71 amino acids
Theoretical weight: 7.86 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-42817
Expression systems:
  • Homo sapiens
  • Escherichia coli
  • Trichoplusia ni