› 8uzo

X-ray diffraction
2.1Å resolution

Crystal Structure of Betaine aldehyde dehydrogenase (BetB) from Klebsiella aerogenes (ADP bound)

Released:
DOI: 10.2210/pdb8uzo/pdb
PDB entry 8uzo coloured by chain, front view.
PDB entry 8uzo coloured by chain, side view.
PDB entry 8uzo coloured by chain, top view.
Source organism: Klebsiella aerogenes KCTC 2190
Entry authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
Betaine aldehyde + NAD(+) + H(2)O = betaine + NADH
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-493941 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Betaine aldehyde dehydrogenase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 499 amino acids
Theoretical weight: 54.06 KDa
Source organism: Klebsiella aerogenes KCTC 2190
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A0H3FPU4 (Residues: 1-490; Coverage: 100%)
Gene names: EAE_13520, betB
Sequence domains: Aldehyde dehydrogenase family

Ligands and Environments

2 bound ligands:
Ligand ADP 4 x ADP
Ligand NA 4 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS-II BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 83.801Å b: 100.578Å c: 123.753Å
α: 90° β: 95.9° γ: 90°
R-values:
R R work R free
0.188 0.187 0.213
Expression system: Escherichia coli BL21(DE3)

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