› 8v0t

Electron Microscopy
3.1Å resolution

SARS-CoV-2 Omicron-XBB.1.5 3-RBD down Spike Protein Trimer 3 (S-GSAS-Omicron-XBB.1.5)

Released:
DOI: 10.2210/pdb8v0t/pdb
PDB entry 8v0t coloured by chain, front view.
PDB entry 8v0t coloured by chain, side view.
PDB entry 8v0t coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Primary publication:
SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition.
Zhang QE, Lindenberger J, Parsons RJ, Thakur B, Parks R, Park CS, Huang X, Sammour S, Janowska K, Spence TN, Edwards RJ, Martin M, Williams WB, Gobeil S, Montefiori DC, Korber B, Saunders KO, Haynes BF, Henderson R, Acharya P
Mol Cell 84 2747-2764.e7 (2024)
PMID: 39059371
Related structures: EMD-42869

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144650 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1284 amino acids
Theoretical weight: 142.23 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 27 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-42869
Expression system: Homo sapiens

Quick links

Citations

1 review citation

Cryo-electron microscopy in the study of virus entry and infection.
Dutta et al. (2024)