› 8v1h

X-ray diffraction
2.89Å resolution

Crystal structure of human pre-mascRNA

Released:
DOI: 10.2210/pdb8v1h/pdb
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PDB entry 8v1h coloured by chain, front view.
PDB entry 8v1h coloured by chain, side view.
PDB entry 8v1h coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of MALAT1 RNA maturation and mascRNA biogenesis.
Skeparnias I, Bou-Nader C, Anastasakis DG, Fan L, Wang YX, Hafner M, Zhang J
Nat Struct Mol Biol (2024)
PMID: 38956168

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-290291 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
pre-mascRNA Chain: A
Molecule details ›
Chain: A
Length: 75 nucleotides
Theoretical weight: 24.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Sequence domains: MALAT1-associated small cytoplasmic RNA/MEN beta RNA

Ligands and Environments

1 bound ligand:
Ligand NA 1 x NA
1 modified residue:
Ligand GTP 1 x GTP

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 22-ID
Spacegroup: C2
Unit cell:
a: 44.986Å b: 40.651Å c: 123.393Å
α: 90° β: 96.99° γ: 90°
R-values:
R R work R free
0.2 0.198 0.246
Expression system: Escherichia coli

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Citations

1 citations in other articles

Structural basis of tRNA recognition by the widespread OB fold.
Umuhire Juru et al. (2024)

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